Dermeva CollagenicBoost Serum
CollagenicBoost™ GHK-CU Serum V2

Your skin knows how to heal. Give it the signal.

Our serum uses your body's own collagen-signaling pathway. Copper peptides that speak the language your skin already understands, to trigger real, measurable repair.

1.5%GHK-CU
1%Collagen Tripeptides
3.0%Vitamin C
2.5%Vitamin B5
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★★★★★ 4.8 out of 5 · 571 verified reviews
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Dermatologist Developed Based on clinical science
Active Formula

Signal. Supply. Repair.

Each ingredient was chosen for a specific role in your skin's collagen production cycle. Nothing is filler.

1.5%
Copper Peptides (GHK-CU)
The natural signaling peptide your body already produces to instruct skin to repair itself and synthesize new collagen. The main driver.
Primary Signal
1%
Collagen Tripeptides
While GHK-CU sends the signal, tripeptides supply the raw building materials, glycine and proline, your skin needs to form new collagen structure.
Building Blocks
3.0%
Vitamin C
A brightening antioxidant and the essential cofactor your skin requires to actually build collagen. Neutralizes daily UV damage. Fades dark spots.
Cofactor + Brightener
2.5%
Vitamin B5
A moisture magnet that pulls water deep into skin, calming redness and keeping skin soft so the peptide repair work isn't undone by dryness.
Moisture + Calm
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★★★★★ 4.8 · 571 verified reviews
Application

Simple. Consistent. Effective.

No complicated 10-step routine. Just four steps, twice a day.

Step 01
Cleanse your face
Start with a gentle cleanser on dry or damp skin. Pat dry, don't rub. Clean skin absorbs actives significantly better.
Morning & Evening
Step 02
Apply 3–5 drops
Dispense 3–5 drops onto your fingertips. A little goes a long way, the serum is highly concentrated by design.
Use Sparingly
Step 03
Press into skin
Gently press the serum into your face and neck using your fingertips. Avoid rubbing, pressing allows better absorption without disrupting the barrier.
No Rubbing
Step 04
Follow with moisturizer
Seal in the serum with your regular moisturizer. This locks in the active ingredients and keeps your skin barrier intact throughout the day or night.
Lock It In
Clinical Evidence

Backed by peer-reviewed research.

GHK-CU is one of the most studied peptides in dermatology. Here's what the science actually shows.

70%
Increase in collagen synthesis
Observed in fibroblast studies with GHK-CU
300+
Genes activated by GHK-CU
Including repair, anti-inflammatory, and antioxidant genes
8×
More effective than retinol
At gene activation for skin renewal pathways
30
Years of published research
On GHK-CU's role in skin biology

GHK-CU is not synthetic, it's biological

GHK-CU (Glycine-Histidine-Lysine-Copper) is a naturally occurring tripeptide found in human blood plasma and tissue. Your body already uses it to initiate wound healing and tissue repair. The serum concentrates it and delivers it directly to the skin surface.

Source: Pickart & Margolina, Rejuvenation Research (2018)

It resets genes to a younger expression pattern

Studies show GHK-CU doesn't just stimulate collagen, it resets the expression of over 300 human genes toward the patterns seen in younger skin. This includes genes governing inflammation control, antioxidant defense, and tissue remodeling.

Source: Pickart et al., BioMed Research International (2015)

Collagen tripeptides close the supply gap

GHK-CU sends the signal, but your skin needs glycine, proline, and hydroxyproline as raw materials to actually synthesize collagen. Our formula includes 1% collagen tripeptides to supply those building blocks directly, a combination rarely found in competing products.

Source: Postlethwaite et al., Journal of Experimental Medicine
Expected Results

What real progress looks like.

Collagen takes time to build. Here's what to expect, honestly.

01
Week 1
Softer. Calmer. A touch firmer.
The serum starts working immediately. Within days your skin will feel noticeably softer, calmer, and a subtle firmness begins.
02
Month 1
Clearer. More even. Refined.
Collagen levels begin increasing measurably. Skin clears, tone evens, dullness lifts. Dark spots fade and texture looks visibly more refined.
03
3+ Months
Maximum collagen. Visible transformation.
Your body has had time to bring collagen to maximum levels. Skin glows, looks visibly firmer. Breakouts become rare and clear fast.
How We Compare

Not all serums are equal.

Most products address symptoms. CollagenicBoost addresses the source.

Feature Dermeva CollagenicBoost™ Retinol Serum Vitamin C Serum Hyaluronic Acid
Triggers collagen productionActivates the body's own repair signal ✓ ✓ — —
Supplies collagen building materialsGlycine, proline, hydroxyproline ✓ — — —
Suitable for sensitive skinNo irritation, peeling, or purging ✓ — — ✓
Brightens and evens toneReduces dark spots and dullness ✓ ✓ ✓ —
Deep hydrationMoisture at the dermal level ✓ — — ✓
Activates gene repair pathwaysResets 300+ genes to younger pattern ✓ — — —
No sun sensitivity increaseSafe for morning use ✓ — — ✓
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571
Verified Reviews
4.8★
Average Rating
90
Day Guarantee
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Customer Reviews

We let our customers speak for us.

4.8
★★★★★ Based on 571 reviews
★★★★★
My skin looks 5 years younger
I started noticing a difference after just two weeks. By month two my texture was completely transformed, the fine lines around my eyes are genuinely less visible. I wasn't expecting this much from a serum.
Sarah M. — Verified Buyer
March 2026
★★★★★
The science actually checks out
As someone who researches ingredients before buying, GHK-CU has solid peer-reviewed backing. What surprised me was how quickly the texture improvements showed up, softer skin within a week, no irritation at all.
James K. — Verified Buyer
February 2026
★★★★★
Finally something that works long-term
Three months in and my skin just glows now. The dark spots I've had for years have faded significantly. My dermatologist actually asked what I'd changed in my routine.
Priya L. — Verified Buyer
January 2026
Questions

Frequently asked.

Most customers notice softer, calmer skin within the first week. Visible improvements in tone and texture typically appear by the end of month one. The most dramatic results, firmer skin, reduced fine lines, even skin tone, come after 3+ months of consistent use as collagen levels reach their peak.
Apply 3–5 drops to clean, dry skin morning and evening. Gently press into face and neck, no rubbing needed. Follow with moisturizer. That's it. No complicated routine required.
We offer a 90-day, no-questions-asked money-back guarantee. If you're not satisfied for any reason within 90 days of purchase, contact us and we'll refund you in full. No return required.
Most serums work on the surface, moisturizing, plumping temporarily, masking issues. CollagenicBoost works at the signaling level: GHK-CU is the same peptide your body produces to initiate skin repair. It doesn't fake collagen, it triggers your skin to produce its own. The collagen tripeptides then supply the raw materials to make that production possible.
Yes, CollagenicBoost is formulated to work across all skin types including sensitive, dry, oily, and combination skin. Vitamin B5 keeps it calming and deeply hydrating, while the formula is fragrance-free and non-comedogenic.
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